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1997 Chrysler Town and Country is missing on number 6 cylinder - already changed the plugs wires fuel injector for 6?

Since you've already replaced the spark plug, wire, and fuel injector for cylinder #6 and the misfire persists, the problem is likely one of the following:

* Damaged Valve: A bent, burned, or otherwise damaged valve in cylinder #6 prevents proper combustion. This is a more significant mechanical issue requiring engine disassembly and repair. A compression test will help diagnose this – low compression in cylinder #6 points strongly to a valve problem.

* Clogged Catalytic Converter: A clogged catalytic converter can restrict exhaust flow, leading to misfires. This is especially likely if the misfire is accompanied by reduced engine power or other performance issues.

* Ignition Coil (Pack): Even if you replaced the spark plug wire, the ignition coil (or coil pack, depending on your engine's setup) for cylinder #6 might be faulty. While less likely if the wire was replaced, it's still possible. A multimeter can test the coil's resistance, or a mechanic can perform a more thorough check.

* Vacuum Leak: A vacuum leak can affect the air/fuel mixture, leading to misfires. This is harder to diagnose but often involves carefully inspecting vacuum lines and hoses for cracks or disconnections.

* PCM/ECM Problem: The Powertrain Control Module (PCM) or Engine Control Module (ECM) could be sending incorrect signals to cylinder #6. This is less likely but possible. A diagnostic scan tool is needed to check for any error codes related to cylinder #6.

* Sensor Issues: Various sensors (e.g., crankshaft position sensor, camshaft position sensor, oxygen sensor) can affect engine performance. Faulty sensors can cause misfires, though it’s less likely to only affect one cylinder.

How to Proceed:

1. Compression Test: This is the most important next step. Low compression in cylinder #6 strongly indicates a valve problem or a significant internal engine issue.

2. Diagnostic Scan: Use an OBD-II scanner to retrieve any trouble codes from the PCM. This might point towards a sensor problem or other electrical issue.

3. Visual Inspection: Carefully inspect all vacuum lines and hoses for cracks or leaks. Check the exhaust system for any blockages or restrictions.

4. Ignition Coil Test (if applicable): Test the ignition coil for cylinder #6 using a multimeter, following the appropriate procedure for your vehicle.

5. Professional Mechanic: If you're not comfortable performing these tests or repairs yourself, it's best to take your vehicle to a qualified mechanic. They have the tools and expertise to diagnose the problem accurately and perform the necessary repairs.

The age of the vehicle makes some repairs more costly to consider than others. A compression test will provide crucial information to guide your next steps and help determine the cost-effectiveness of further diagnosis and repair.