You'll find the best information by looking up the specific engine size listed on your vehicle's documentation (usually found in the owner's manual or on a sticker in the driver's side doorjamb). Once you know the engine, you can search online for EPA estimates of MPG for that specific 2006 Dodge Caravan model and engine.
Generally speaking, expect figures in the range of:
* City MPG: 16-21 mpg
* Highway MPG: 22-25 mpg
These are just estimates. Actual mileage will be affected by factors like driving style, terrain, vehicle condition, and tire pressure. The lower end of the range is more likely if you frequently drive in city traffic or have a heavier load.