* Wheel well clearance: 22-inch rims with tires will have a much larger overall diameter than the stock wheels. This will likely cause rubbing against the fenders, suspension components, or body of the car.
* Offset and backspacing: The offset (how far the wheel's mounting surface is from its center) and backspacing (the distance from the mounting surface to the inner edge of the rim) are crucial. A 22-inch rim might have dimensions incompatible with the Impala's hub and suspension geometry. Incorrect offset can cause handling issues and damage to the car.
* Tire sidewall height: To fit larger rims, you'd likely need to use tires with very low-profile sidewalls. This drastically reduces ride comfort and makes the car much more susceptible to damage from potholes and bumps.
While some people *do* fit larger wheels on cars than what's recommended, it typically requires significant modifications (like fender rolling, possibly even cutting into the bodywork, and potentially altering the suspension). These modifications are expensive, may compromise the structural integrity of the car, and can be illegal depending on local regulations.
In short: Don't expect a 22-inch rim to fit a 2007 Chevy Impala easily, or safely without extensive and potentially damaging modifications. Sticking to recommended wheel sizes is always the safest and most practical approach. Check your owner's manual or consult a tire specialist for the correct wheel size recommendations for your Impala.