The main fuse panel (also called the Power Distribution Center or PDC) on a 2006 Dodge Ram 2500 is located
under the hood, on the driver's side. It's usually a large black box. You'll likely see numerous fuses and relays inside.
It's important to note that there might also be a smaller fuse panel inside the cab, typically under the dashboard. That panel handles interior circuits. The one under the hood is for the main power distribution to the truck.