You'll likely need a repair manual or a diagram specific to your vehicle's year and engine to pinpoint its exact location. A picture search online for "2000 Chevy S10 4.3L temperature sensor location" might also prove helpful. Be aware there may be multiple sensors in that area – coolant temperature sensor, for example – so you want to be sure you are finding the *temperature switch* specifically. The temperature switch is often the one connected to the gauge in the instrument cluster, controlling the temperature gauge.