To find it, you need to consult your owner's manual. The manual will have a diagram showing the fuse box layouts and identifying which fuse is for the trailer wiring (often labeled something like "trailer tow," "tow," or a similar designation).
If you don't have your owner's manual, you can usually find a digital version online by searching "[Your Ford F250 Year] Owner's Manual" on Google or Ford's website. You'll need to know the exact year and model (e.g., F-250 Super Duty XLT, 2018) for accurate results.