To be absolutely sure, you should:
* Consult your owner's manual: This is the best source for precise information about your specific vehicle.
* Check online repair manuals: Sites like Chilton or Haynes offer detailed diagrams and instructions. Search for "2000 GMC Safari fuel filter location" on their websites.
Because you're working with fuel, safety precautions are essential. Always disconnect the negative battery terminal before attempting any fuel system work.