* Electrical Differences: The biggest potential hurdle is the difference in the transmission's electronic controls. The 4L60E evolved over the years, and the 2000 model likely has a different PCM (Powertrain Control Module) communication protocol and potentially different sensor configurations than the 1994 system. This could lead to transmission operation problems, shift issues, or even damage to the transmission or PCM.
* Mechanical Differences: While the basic mechanical design is similar, there might be minor differences in valve bodies, internal components, or even the bellhousing bolt pattern (though less likely between years within the same transmission family).
* Torque Converter: The torque converter needs to be compatible with both the engine and the transmission. Using the wrong torque converter can lead to damage.
In short: It's risky. While it *might* bolt up, it's highly probable that the electrical incompatibility will prevent it from functioning correctly, potentially damaging the transmission or even the engine's PCM. It's far safer and more reliable to source a 4L60E transmission from a similar model year (1994-1997) to ensure compatibility. Even then, a professional inspection and possibly some reprogramming might be needed.
Before attempting such a swap, consult with a transmission specialist or a mechanic experienced with GM transmissions to assess the feasibility and potential risks involved.