Generally, you can expect significantly lower MPG than smaller vehicles. Older models with larger engines will have considerably worse fuel economy than newer models with more efficient engines or hybrid options.
To get a precise estimate, you should specify:
* Year: (e.g., 2023, 2020, 2015)
* Engine: (e.g., 6.2L V8, 3.0L Turbo Diesel, Hybrid)
Once you provide this information, I can give you a more accurate estimate based on EPA fuel economy ratings. You can also find this information by searching online for "[Year] Cadillac Escalade EPA fuel economy"