Autobots
- Bumblebee: Chevrolet Camaro (2007-2018), Chevrolet Bumblebee (2019-present)
- Optimus Prime: Peterbilt 389 series truck (2007-2017), Freightliner Cascadia (2018-present)
- Ironhide: GMC TopKick C4500 pickup (2007-2011)
- Ratchet: Search and rescue Hummer H2 (2007-2011), Chevrolet Suburban (2014)
- Jazz: Pontiac Solstice (2007)
- Sideswipe: Chevrolet Corvette Stingray C6 (2009)
- Arcee: Ducati 848 (2009)
- Chromia: Saleen S7 (2009)
- Elita-One: Cybertronian pickup truck (2018)
- Hot Rod: Chevrolet Camaro (1967) (2018)
- Drift: Mercedes-AMG GT R (2014), Mercedes-AMG S63 Cabriolet (2017)
Decepticons
- Megatron: Cybertronian jet (2007-2009), Mack MP10 tractor-trailer (2011-2017)
- Starscream: Cybertronian jet (2007-2011), Lockheed SR-71 Blackbird (2017-present)
- Blackout: Sikorsky MH-53 Pave Low (2007)
- Barricade: Saleen S281 Mustang Police Interceptor (2007)
- Frenzy: Radio control car (2007)
- Scorponok: Giant scorpion (2007)
- Devastator: Combined form of Mixmaster, Scrapper, Overload, Scavenger, Hightower, and Long Haul (2009)
- Shockwave: Cybertronian tank (2011)
- Soundwave: Cybertronian communications vehicle (2011-2014), Mercedes-Benz SLS AMG (2014)
- Laserbeak: Cybertronian condor (2011-2014)
- Ravage: Cybertronian panther (2011)
- Blitzwing: McDonnell Douglas F-4 Phantom (2011)
- Lockdown: Cybertronian bounty hunter (2014)
- Galvatron: Megatron (2014-2017)
- Unicron: Cybertronian planet (2018-present)
Other Vehicles
- Sam Witwicky's car: 1976 Chevrolet Camaro (2007-2011), 2011 Chevrolet Camaro SS (2014)
- Mikaela Banes's car: 1970 Chevrolet Camaro SS (2007)
- Bumblebee's motorcycle: 2009 Ducati 848 (2009)
- Dino's car: 1987 Buick GNX (2009)
- Seymour Simmons's car: 1972 GMC Sierra Grande pickup truck (2009)
- Carly Spencer's car: 2014 Mercedes-Benz SLS AMG (2014)
- Cade Yeager's truck: 1967 Chevrolet C-10 pickup truck (2014)
- Izabella's car: 1987 Lamborghini Countach (2017)
- Charlie Watson's car: 1967 Volkswagen Beetle (2018)
- Jack Burns's car: 1972 AMC Javelin (2018)
