According to the Lexus ES300 owner's manual, when the low fuel light illuminates, you have approximately
2.4 gallons of fuel remaining in your vehicle's tank. Depending on your driving conditions, this should allow you to travel an additional
35-50 miles before completely running out of fuel.
However, it's essential not to push your luck and always refuel your vehicle as soon as possible when the low fuel light turns on. Continuing to drive with a low fuel level can strain the fuel pump, leading to premature failure and potentially more significant problems down the road.