R-22 is not compatible with R-12 systems for a number of reasons. First, R-22 has a higher boiling point than R-12, which means that it will not evaporate as easily in the evaporator. This can lead to a loss of cooling capacity. Second, R-22 has a higher pressure than R-12, which can put stress on the compressor and other components of the AC system. Third, R-22 is not compatible with the mineral oil that is used in R-12 systems. This can lead to leaks and other problems.
For all of these reasons, it is not advisable to use R-22 in an R-12 AC system. If you are looking to replace the refrigerant in your AC system, you should contact a qualified technician who can recommend a suitable replacement refrigerant.