A stock, small-block 350 from the 1960s might have produced anywhere from around 195 to 300 horsepower, depending on the application (truck, car, etc.) and the specific carburetor and other options. Later versions (even stock ones) would have different horsepower ratings.
Highly modified 350s can produce far more than 300 horsepower, easily exceeding 500 or even 1000 horsepower with significant modifications.
Therefore, you need to provide more specifics about the engine to get a more accurate horsepower estimate.