* Engine mounts: Completely different mounts would be required.
* Wiring harness: The 5.4L's harness is incompatible.
* Exhaust system: The exhaust manifolds and piping would need to be custom-fabricated.
* Cooling system: Potentially a larger radiator and different hoses.
* Power steering lines and components: May need modification or replacement due to clearance issues.
* Air intake system: Likely requires significant modification or replacement.
Regarding the transmission: Even if you *could* fit the 5.4L, the stock automatic transmission is *highly unlikely* to handle the extra power reliably. The 5.4L produces considerably more torque than the 4.6L, putting significant stress on the transmission, potentially leading to premature failure. You'd almost certainly need a stronger transmission, likely requiring a complete swap to a unit designed for higher torque output.
In short, this swap is a major undertaking, far beyond a simple bolt-in affair. It would require significant fabrication, custom parts, and expertise in automotive mechanics. The cost and effort would likely far exceed the potential gains.