* V8 (8-cylinder): This was the most prevalent engine option. There were variations in displacement (size), but they were all V8s.
* V6 (6-cylinder): Less common than the V8, but some E-350s were equipped with a V6 engine.
To know the *specific* cylinder configuration of a particular 1997 Ford E-350, you need to check the vehicle's documentation (like the owner's manual or the vehicle identification number (VIN) decoding).