* Weak Battery: This is the most common cause. A weak battery struggles to provide enough power to turn the engine over quickly. Have the battery tested at an auto parts store; a simple voltage test isn't enough; they need to perform a load test.
* Bad Battery Cables/Connections: Corroded, loose, or damaged battery cables or connections prevent the full current from reaching the starter motor. Inspect them carefully for corrosion, looseness, and damage. Clean any corrosion thoroughly.
* Failing Starter Motor: A worn-out starter motor struggles to engage and turn the engine. This is a common issue as starters wear down over time, especially in larger trucks. It might click weakly or make grinding noises.
* Low Engine Compression: While you have spark and fuel, low compression means the engine is struggling to ignite the air/fuel mixture effectively. This can cause a slow crank and ultimately failure to start. A compression test is needed to diagnose this.
* Stuck or Broken Engine Components: A seized piston, damaged connecting rod, or other internal engine failure can create significant resistance, making the engine difficult to turn over. This is less likely if it used to run fine.
* Thick Engine Oil: Extremely thick or incorrect engine oil can increase resistance, leading to slow cranking. However, this typically wouldn't result in a *sudden* inability to start.
* Faulty Neutral Safety Switch (NSS): If the transmission isn't in park or neutral (depending on your truck's setup), the NSS prevents the starter from engaging. This would prevent the engine from turning over at all, though.
Troubleshooting Steps:
1. Battery Test: This is the absolute first step. Get a load test, not just a voltage check.
2. Cable Inspection: Visually inspect all battery cables and connections for corrosion, damage, and tightness. Clean and tighten as needed.
3. Starter Motor Check: Listen closely while trying to crank the engine. Any unusual clicking, grinding, or whining sounds point to a starter motor problem. A mechanic may be needed to test this properly.
4. Compression Test (if other steps fail): A compression test can determine if there's a problem with the engine's internal components. This requires specialized tools.
If you're not comfortable performing these checks yourself, take your F-250 to a qualified mechanic for diagnosis and repair. It's best to start with the simplest and most common issues (battery and cables) before moving on to more complex problems.