The best way to adjust the jetting on your carburetors is to use a dyno. This will allow you to measure the air/fuel ratio at different throttle positions and RPMs, and make adjustments to the jetting until the engine is running at its best.
If you do not have access to a dyno, you can also try to adjust the jetting by ear. Start by setting the air/fuel mixture screw to the richest setting. This will make the engine run rich, but it is better to start rich and then lean it out as needed.
Once the engine is running, listen to the sound of the exhaust. If the exhaust sounds popping or crackling, then the mixture is too lean. If the exhaust sounds muffled or has a low gurgling sound, then the mixture is too rich.
Continue to adjust the air/fuel mixture screw until the engine sounds smooth and responsive. You may also need to adjust the idle mixture screw and the main jet size to get the engine running at its best.
It is important to note that adjusting the jetting on your carburetors can be a complex and time-consuming process. If you are not confident in your ability to do it yourself, I would recommend taking your bike to a qualified mechanic.