$$ Cost = (Distance / MPG) * Cost per gallon $$
Plugging in the given values, we get:
$$ Cost = (1600 miles / 12 MPG) * $3.95/gallon $$
$$ Cost = 133.33 gallons * $3.95 $$
$$ Cost = $526.17 $$
Therefore, it will cost approximately $526.17 to drive 1600 miles getting 12 miles the gallon at $3.95 a gallon.