Yes, the transmission fluid in your 2001 Toyota Camry should be changed periodically as part of regular maintenance. The recommended maintenance schedule for your vehicle may vary depending on factors such as driving conditions and mileage, but generally, the transmission fluid should be changed every 30,000 to 60,000 miles or every two to three years, whichever comes first.
Note: If your Camry is equipped with a continuously variable transmission (CVT), it may have different transmission fluid maintenance requirements; please refer to your owner's manual or consult with a reputable mechanic for specific guidelines.