1. Start from San Jose and head east on Interstate 280.
2. Take the Interstate 680 South ramp.
3. Merge onto Interstate 680 South and continue for about 18 miles.
4. Take the Interstate 580 East ramp and merge onto Interstate 580 East.
5. Follow Interstate 580 East for approximately 82 miles.
6. Take the Modesto exit (Exit 41A) and follow the signs to Modesto.
This route is the most direct and fastest way to drive from San Jose to Modesto. It takes you through pleasant scenery, including rolling hills and farmland. Along the way, you can also stop at various rest stops or gas stations if needed.