* Spark Plug: A fouled, damaged, or improperly gapped spark plug.
* Ignition Coil: A failing ignition coil (if your S10 uses individual coils per cylinder) or a problem with the coil pack (if it uses a coil pack).
* Worn or Leaking Injector: A clogged, leaky, or failing fuel injector in cylinder 2.
* Worn Valve: A worn or damaged valve in cylinder 2, preventing proper combustion.
* Vacuum Leak: A vacuum leak affecting cylinder 2's intake.
* Low Compression: Low compression in cylinder 2.
* Damaged or Faulty Wiring: Problems with the wiring to the spark plug or injector for cylinder 2.
To diagnose the issue, a mechanic will likely start by checking the basics: spark plugs, wires, and the ignition coil (or coil pack) for cylinder 2. They may also perform a compression test to check the cylinder's compression and a fuel pressure test to ensure adequate fuel delivery. A scan tool can help pinpoint exactly when the misfire is occurring (e.g., at idle, under load, etc.), which can give further clues.