Can you put a 2-wheel drive transmission in 4-wheel truck and it still be drive?

No, you can't simply put a 2-wheel drive transmission in a 4-wheel drive truck and expect it to drive. The transfer case, which is integral to a 4WD system, is designed to work with the 4WD transmission. A 2WD transmission lacks the necessary components to engage and disengage the front driveshaft, and the output shaft likely won't be compatible with the transfer case. Trying to force it would likely cause damage to the transmission, transfer case, or other drivetrain components. You'd need a complete 2WD drivetrain (transmission, transfer case, driveshafts, differentials) to make it work, and even then, significant modifications might be necessary depending on the truck model.