* Suspension and Handling: The Town Car's suspension isn't designed for such large rims and the accompanying low-profile tires. This will result in a very harsh ride, significantly reduced comfort, and potentially damage to the suspension components. You'll likely experience much more jarring from bumps and potholes.
* Wheel Well Clearance: 22-inch rims with tires might rub against the fenders, particularly during turns or with passengers and cargo. You might need extensive modifications (e.g., fender rolling, possibly even body modifications) to avoid this.
* Speedometer Calibration: Larger wheels will affect the speedometer's accuracy, making it read slower than your actual speed.
* Brakes: Depending on the specific brake setup, there could be clearance issues with the larger wheels and calipers.
* Cost: 22-inch rims are expensive, and you'll likely need modifications and new tires, which will add significantly to the cost.
In short, while technically feasible, it's a bad idea. It's far more sensible to stick to wheel sizes within the manufacturer's recommendations for a comfortable and safe driving experience. Going up a size or two might be acceptable depending on the model year, but 22 inches is a drastic change for a Town Car.