You cannot simply guess. The best way to ensure correct installation is to:
1. Refer to a repair manual: A Haynes or Chilton manual specific to your year and engine will show a diagram and describe the proper installation. This is the most reliable method.
2. Examine the old thermostat: Before removing the old thermostat, carefully note its orientation in the housing. Take a picture if needed.
3. Look for markings: The thermostat itself or the housing may have markings indicating the correct orientation (though this isn't always the case).
Installing the thermostat incorrectly can lead to poor engine cooling, overheating, and serious engine damage. If you're uncertain, seeking professional help from a mechanic is recommended.