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Will a Chevy 350 cam fit in Buick 350?

No, a Chevy small-block 350 camshaft will not directly fit a Buick 350. While both are 350 cubic inch V8s, they have significantly different block designs and camshaft specifications (lobe separation, lifter geometry, etc.). The camshaft journals, lifter bores, and even the overall camshaft dimensions are incompatible.