However, the exact location can vary slightly depending on the engine (4.3L V6, 5.7L V8, etc.). You'll need to consult a repair manual specific to your Blazer's engine to get the precise location. A Chilton's or Haynes manual will have diagrams showing the sensor's placement. You can also find diagrams online by searching for "[your Blazer's engine size] oxygen sensor location."
Be aware that the sensor is threaded into the exhaust system and may be difficult to access. You'll likely need a socket and possibly an extension to reach it.