Estimated miles per gallon on a Chevrolet s10 4.3 v6?

The EPA estimated MPG for a Chevrolet S10 with a 4.3L V6 varies significantly depending on the year of manufacture, transmission type (automatic or manual), and whether it's a regular cab, extended cab, or crew cab. Also, driving conditions and maintenance greatly affect real-world MPG.

However, you can generally expect to see figures in the range of:

* City: 14-17 mpg

* Highway: 18-22 mpg

This is just an estimate. To get a more precise idea for a specific year and model, you should consult the original owner's manual or a reliable source like the EPA's fueleconomy.gov website (you'll need to input the year and model details). Real-world mileage will likely be lower than the EPA estimates.