Where is the radiator drain plug on a 2000 Chevy S-10 4x4 4.3 liter V6?

The radiator drain plug on a 2000 Chevy S-10 4x4 with a 4.3L V6 is located at the bottom of the radiator, on the driver's side. It's usually a small, threaded plug. You might need a wrench (likely a 9/16" or 11/16"; it's best to check before starting). However, *always consult your owner's manual for the precise location and size*. The manual will provide diagrams and specific instructions to ensure you drain the coolant properly without causing damage.