* Engine mounts: The Buick 455's bellhousing bolt pattern and engine mount locations are completely different from a Chevy small-block or big-block. Custom engine mounts will need to be fabricated.
* Transmission: The transmission used will likely need to be adapted. The Buick 455's bellhousing won't match a typical Chevy transmission. You might need an adapter plate or a transmission from a Buick.
* Exhaust system: The exhaust manifolds or headers will need to be custom-made or heavily modified to fit the Chevy frame and body.
* Steering: The Buick engine's size and location might interfere with the steering components, requiring adjustments or modifications.
* Wiring: The wiring harness will need to be adapted or completely rewired to fit the Chevy's electrical system.
* Radiator: The radiator might need to be upgraded or relocated to accommodate the larger engine.
In short, while not impossible, it's a major undertaking requiring significant mechanical skills, fabrication abilities, and potentially considerable expense. It's not a weekend project. Many people looking for a powerful engine in a Chevy truck choose a more readily compatible big-block Chevy engine instead.