Removing the bed is a significant undertaking, requiring the removal of numerous bolts, taillights, wiring harnesses, and potentially other components. Dropping the tank, while involving some work (fuel line disconnection, electrical connections, tank straps), is a considerably less involved process. Even with a full tank, you can partially drain it to make it lighter.
Therefore, dropping the tank is the recommended approach. The time saved far outweighs the minor inconvenience of dealing with a full tank.