It's always best to:
* Check your owner's manual: This is the definitive source for your specific vehicle.
* Check the battery itself: The battery group size is usually printed on a label on top of the battery.
* Consult a local auto parts store: They can look up the correct battery for your vehicle by your VIN number.
While Group 51R is the most likely answer, using one of the above methods will ensure you get the precisely correct battery for your 2006 Ford Escape 4-cylinder.