When was the first car on road?

There's no single definitive answer to when the "first car" was on the road, as it depends on how you define "car." The invention of the automobile was a gradual process with many contributors.

However, Karl Benz's Patent-Motorwagen from 1886 is widely considered to be the first practical automobile. While other vehicles with internal combustion engines existed before, Benz's was the first to be designed specifically as a self-propelled vehicle for personal use and was commercially successful (though in very small numbers initially).