* Motor Mounts: The Chevy 350 uses completely different motor mounts than the Buick V6 or V8 that originally came in the Skylark. You'll need custom motor mounts fabricated or purchased aftermarket.
* Transmission: The transmission needs to be compatible with the Chevy 350. A Chevy small-block transmission (like a TH350, TH400, or 700R4) will be needed, and the transmission crossmember will likely need modification or replacement.
* Exhaust System: The exhaust system will need to be custom-fabricated to fit the Chevy engine's exhaust manifolds or headers.
* Steering: The steering linkage may interfere with the larger Chevy engine. Adjustments or modifications might be needed.
* Wiring Harness: The Skylark's wiring harness is designed for its original engine and will not be compatible with the Chevy 350. A new wiring harness will either need to be fabricated or sourced (aftermarket harnesses exist for this swap but require some wiring expertise.)
* Radiator: The stock radiator might be insufficient for cooling the larger Chevy 350 engine. A larger capacity radiator might be necessary.
In short, while it's *possible*, it's a significant undertaking requiring fabrication, mechanical knowledge, and possibly some custom parts. It's not a simple bolt-in swap. Many experienced mechanics have done this swap successfully, but it's not a project for a novice.
