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Can synthetic blend 530 be used on a 2006 ford 150 5.4 L?

Yes, a synthetic blend 5W-30 oil is generally suitable for a 2006 Ford F-150 with a 5.4L engine. However, always check your owner's manual. It will specify the recommended oil viscosity and type (conventional, synthetic blend, or full synthetic). While 5W-30 is a common recommendation, the manual might specify a different weight or type depending on your climate and driving conditions. Using the wrong oil can damage your engine.