* Same Engine Family, Likely Yes: If both Blazers have the same engine family (e.g., both are 4.3L V6s, both are 5.7L V8s), there's a high chance of compatibility. However, even within the same family, there might be minor differences in mounts, sensors, or accessories that require some adaptation.
* Different Engine Family, Possibly Yes, But More Challenging: If the engines are from different families (e.g., swapping a 4.3L V6 for a 5.7L V8, or a different generation of the same engine size), it becomes much more complex. You'll likely need to replace or modify engine mounts, wiring harnesses, and possibly the transmission and driveshaft.
In short: You'll need to know the *exact* engine codes (found on a sticker on the engine block) for both Blazers to determine compatibility. Even then, some fabrication or adaptation might be necessary. Consulting a mechanic or a parts professional with experience in this area is highly recommended before undertaking such a swap.
