To be certain, you'll need to:
1. Consult your vehicle's repair manual: This is the most reliable source. The manual will have diagrams showing the exact location.
2. Look for a sensor with one or two wires connected to it: It's usually a relatively small sensor near the oil filter.
3. Use online resources: Search for images of "5.3L Chevy oil pressure sensor location [year of your vehicle]" on Google Images or YouTube. Be sure to double-check the year to ensure you're looking at the correct engine.
Remember to be careful when working around the engine. Make sure the engine is cool and disconnect the negative battery terminal before working on any engine components.