* Maintenance: Regular oil changes, proper fluid levels, and timely repairs are crucial. Neglect leads to premature wear.
* Driving habits: Aggressive driving, frequent towing, and short trips put more stress on the engine.
* Operating conditions: Extreme temperatures, dusty environments, and off-road use can accelerate wear.
* Previous repairs/rebuilding: A previously repaired or rebuilt engine might have a shorter lifespan than a completely original one.
While some 4.3L engines in Blazers might reach 200,000 miles or more with excellent maintenance, others might fail much sooner due to the factors listed above. You'll find anecdotal evidence online of both extremes. Averages are unreliable in this context.
Instead of focusing on a mileage target, prioritize regular maintenance to maximize the engine's lifespan.