To be absolutely certain, you should:
* Consult a repair manual: A Haynes or Chilton manual specific to your year and model will have diagrams showing the exact location of all sensors.
* Use a Ford parts diagram: Ford's website or a reputable online parts supplier (like AutoZone, Advance Auto Parts, etc.) will have diagrams for your vehicle. Searching for "2000 Ford F250 7.3L Powerstroke engine diagram" will be helpful.
* Search online: Images from other 2000 F250 7.3 Powerstroke owners who've worked on their engine can help you visually identify the sensor. Be sure to double-check the year and engine to ensure accuracy.
Visually inspecting the intake manifold area after locating diagrams will be the most reliable way to find the sensor.