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Can you use pistons from a 2 bolt main Chevy in 4 block?

No, you cannot directly use pistons from a 2-bolt main Chevy small block in a 4-bolt main Chevy small block. While they might *appear* similar, there are crucial differences in the block's deck height and possibly the piston's design that will prevent proper installation and function. Attempting to do so would likely result in severe engine damage.