Yes, a used Power Control Module (PCM) for a 2001 Dodge Intrepid 2.7L engine almost certainly needs to be reprogrammed. While it might *appear* to function initially, it's highly unlikely to be correctly matched to your vehicle's specific configuration (VIN, options, etc.). Attempting to use it without reprogramming could lead to drivability issues, poor performance, or even damage to other components.
The PCM contains the vehicle's specific calibration data, and this data is unique to each vehicle. A used PCM from another vehicle will have different calibration data, making it incompatible. You'll need to have it programmed with the correct calibration data for your car's VIN using a professional scan tool. This is usually done by a qualified mechanic or at a dealership.