Do not attempt this unless you are a qualified mechanic with the proper training and tools.
That being said, the general steps *typically* involve these procedures, but there may be variations depending on the year and model of the F-350:
1. Disconnect the battery: This is crucial to prevent accidental airbag deployment.
2. Remove the airbag: This requires specialized tools and knowledge of the airbag system to avoid accidental deployment and injury. The procedure varies greatly depending on the year of your truck. There are videos available online, but proceed with extreme caution.
3. Remove the steering wheel nut: This usually requires a special steering wheel puller tool.
4. Remove the steering wheel: After the nut is removed, the steering wheel can be pulled off. This may require some force and the use of a steering wheel puller.
5. Disconnect the clock spring (spiral cable): This is the crucial component allowing the steering wheel to rotate freely without disconnecting electrical signals to the horn, airbag, and cruise control. This step requires careful attention.
Again, I strongly advise against attempting this yourself. If you need your steering wheel removed, take your F-350 to a qualified mechanic or dealership. They have the proper tools, experience, and knowledge to do the job safely and correctly. Improper removal can result in serious damage and safety hazards.