No, 6-lug GM wheels will almost certainly *not* fit on Jeep Wagoneer axles. While both might be 6-lug, the bolt pattern (the distance between the lug holes) and the center bore (the hole in the center of the wheel that fits over the hub) are almost certainly different. Even if the lug pattern *were* the same, the center bore is unlikely to match. Using the wrong wheels could lead to serious safety issues.
To ensure compatibility, you need to determine the bolt pattern and center bore of both your Jeep Wagoneer axles and the GM wheels. This information is usually found stamped on the wheel itself or in your vehicle's owner's manual. If the bolt pattern and center bore don't match exactly, the wheels won't fit safely.