* Space Constraints: The engine bay in an S10 is relatively cramped, making access to bolts and components difficult. You'll likely be working in awkward positions.
* Numerous Connections: You'll need to disconnect numerous components, including the driveshafts, linkage, shifter cables, cooling lines, electrical connectors, and the torque converter. Misplacing or damaging these during removal can lead to significant problems later.
* Weight and Size: The transmission itself is heavy and bulky. You'll need adequate lifting equipment and possibly assistance to safely maneuver it out from under the vehicle. A transmission jack is practically essential.
* Potential for Damage: There's a risk of damaging surrounding components if you're not careful during disassembly and removal.
* Specialized Tools: While basic hand tools are needed, you'll also likely need specialized tools like a transmission jack, torque wrench, and possibly a flywheel puller (depending on the type of transmission and clutch).
In short: Unless you have significant experience working on vehicles, particularly transmissions, it's strongly recommended you seek professional help. Attempting this yourself without the proper knowledge and tools could lead to damage to your vehicle and potential injury. A professional mechanic will have the expertise, tools, and experience to do the job safely and efficiently. The cost of professional labor will be significantly less than the potential cost of repairs if you damage something in the process.