1. Spark plug issues: Worn or damaged spark plugs can cause misfires and rough running. Inspect the spark plugs and replace them if necessary.
2. Ignition coil issues: Faulty ignition coils can also cause misfires. Check the ignition coils and replace them if necessary.
3. Fuel injector issues: Clogged or dirty fuel injectors can cause a lack of fuel to the engine, resulting in misfires and rough running. Clean or replace the fuel injectors as necessary.
4. Vacuum leaks: A vacuum leak can cause a lean fuel mixture, which can lead to misfires and rough running. Inspect the vacuum hoses for leaks and repair or replace them.
5. Compression issues: Low compression in one or more cylinders can cause misfires and rough running. Perform a compression test to check the compression and repair or replace the engine as necessary.