```
Gas required (in gallons) = Distance (in miles) / Fuel efficiency (in miles per gallon)
```
Plugging in the values given in the question:
```
Gas required = 600 miles / 25 miles per gallon
= 24 gallons
```
Therefore, it will take approximately 24 gallons of gas to drive 600 miles with a fuel efficiency of 25 miles per gallon.