* 5R110W: A five-speed automatic transmission. This was the most prevalent option.
* 6-speed manual: A six-speed manual transmission was also available, but less common than the automatic.
To know for certain which transmission a specific 2008 F-250 Super Duty has, you'd need to check the vehicle's specifications (often found on a sticker inside the driver's side door jamb) or the owner's manual.