The blower resistor on a 2000 Chevy Blazer is typically located
behind the glove box. You'll likely need to remove the glove box to access it. However, the exact location can vary slightly depending on trim level and whether your Blazer has air conditioning. Some are mounted on the blower motor housing itself.
Before you start dismantling anything, it's a good idea to consult a repair manual specific to your 2000 Chevy Blazer. A wiring diagram will be very helpful in pinpointing the resistor. You can often find these online or at auto parts stores.