However, it's not always clearly labeled. You'll need to consult your owner's manual or a wiring diagram to identify the specific relay. The manual will have a fuse/relay diagram showing locations and often a description of what each relay controls.
If you don't have the owner's manual, you can often find a downloadable version online through the Chevrolet website or a third-party auto repair manual provider. Searching online for "2001 Chevy Impala 3.8L fuse box diagram" will also yield results. Look for the relay that is described as controlling the fuel pump or the fuel injection system.