* Spark Plug: Even if the wires are new, the spark plug itself could be faulty (cracked insulator, worn electrode, etc.). Replace the spark plug in cylinder #6. This is the simplest and most common cause after the wires.
* Ignition Coil: Many modern engines use coil-on-plug (COP) systems, meaning each cylinder has its own ignition coil. A faulty coil for cylinder #6 will prevent spark. If your engine uses a COP system, replace the coil for cylinder #6. If it uses a distributor, inspect the distributor cap and rotor for cracks, wear, or damage.
* Crankshaft Position Sensor (CKP) or Camshaft Position Sensor (CMP): These sensors tell the engine's computer where the pistons are in their cycle, which is crucial for proper ignition timing. A faulty sensor can cause misfires or lack of spark in one or more cylinders. These are more involved to test and replace. You might need an oscilloscope or advanced scan tool to properly diagnose them.
* Wiring Harness: Though you've replaced the wires, there might be a break or short in the main wiring harness leading to the coil or spark plug for cylinder #6. Visually inspect the harness for damage, especially near the cylinder head.
* PCM (Powertrain Control Module) or ECU (Engine Control Unit): While less likely, a fault within the engine's computer could be the cause. This is usually diagnosed after other components have been ruled out and often requires specialized tools and expertise.
Troubleshooting Steps:
1. Replace the Spark Plug: This is the easiest and cheapest first step.
2. Inspect the Ignition Coil: Visually inspect for damage (cracks, burns). If using a COP system, swap it with a known good coil from another cylinder (if possible) to see if the misfire moves.
3. Check for Wiring Issues: Carefully inspect the wiring harness for any breaks, shorts, or corrosion, focusing on the area connected to cylinder 6.
4. Check for Diagnostic Trouble Codes (DTCs): Make sure you've read *all* the DTCs from the scan tool, not just those related to cylinder 6. Other codes might hint at the root cause.
Important Note: Always disconnect the negative battery terminal before working on any ignition system components to prevent electrical shocks and damage. If you're not comfortable working on your car's electrical system, consult a qualified mechanic.
