Has anyone ever had a 98 Chevy S10 stop running while driving-- First the odometer light flickers then car just turns off like someone took key out of ignition?

Yes, this is a classic symptom of a failing ignition switch in a 98 Chevy S10 (and other GM vehicles of that era). The flickering odometer light is a strong indicator that the ignition switch isn't providing consistent power. When it fails completely, the engine dies as if the key was removed.

Other potential causes, though less likely given the odometer light symptom, include:

* Faulty ignition coil: While less common to cause a complete shutdown *with* the odometer light flickering, a failing coil can interrupt the spark to the engine.

* Alternator problems: A failing alternator won't directly cause the odometer to flicker, but if it's completely dead, the battery will drain quickly, leading to a sudden shutdown. This scenario is less likely given the specific sequence you describe (flickering light, then shutdown).

* Poor wiring connections: A loose or corroded connection somewhere in the electrical system could be causing intermittent power loss. This is also less likely to directly correlate with the odometer light behavior.

* PCM (Powertrain Control Module) issues: A failing PCM is possible, but less probable as the primary cause in this situation.

However, the ignition switch is the most likely culprit given the described symptoms. It's a relatively common problem on these vehicles. Replacing the ignition switch is usually the first step in troubleshooting. A qualified mechanic can diagnose the problem accurately and efficiently, but the ignition switch is a fairly common and inexpensive repair if that's the issue.